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(The Guest Editors of this issue invited four experts with relevant research experience Dr. Chrispin Kambili from International AIDS Vaccine Initiative Africa; Professor William Muraskin of Queens College, CUNY, New York; Professor Lynn K. Mytelka of UNU-INTECH, Maastricht and Luigi Orsenigo from University of Brescia and CESPRI, Bocconi University, Milan to discuss the significance of vaccine initiatives in developing countries for long-term capacity development. Following are their views.)